On Sacred Ground is based on the true events during the 2016 construction of the Dakota Access Pipeline that runs through the Standing Rock Indian Reservation. The film follows Daniel (William Mapother), a journalist and military veteran, and Elliot (David Arquette), an oil company executive, who find themselves on opposite sides of the fight during the construction of the contentious pipeline. As the story unfolds, the two characters go down separate paths during one of the most heated protests and confrontations with Native American tribes in modern US history.